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Nifedipine-induced gingival hyperplasia.

E J Burkes, J R Jacoway, D T Stevens

    The Journal of the Tennessee Dental Association
    |April 11, 1992
    PubMed
    Summary

    Nifedipine, a calcium channel blocker used for heart conditions, can cause severe gingival hyperplasia. This condition, or overgrowth of gum tissue, significantly impacted a patient

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    Area of Science:

    • Pharmacology
    • Periodontology
    • Cardiology

    Background:

    • Nifedipine is a widely prescribed calcium channel blocker for managing hypertension and cardiac conditions.
    • Gingival hyperplasia is a known, albeit infrequent, side effect associated with nifedipine use.

    Observation:

    • A 43-year-old male patient with hypertension developed severe gingival hyperplasia during active dental treatment.
    • The condition progressed to a degree that necessitated modifications to his dental care plan.

    Findings:

    • The patient's gingival hyperplasia was directly linked to his nifedipine medication.
    • Discontinuation of nifedipine and transition to alternative antihypertensive drugs led to the resolution of gingival overgrowth.

    Implications:

    • Highlights the importance of considering medication side effects in dental treatment planning.
    • Emphasizes the need for interdisciplinary communication between cardiologists and dentists.
    • Suggests prompt drug review and modification can effectively manage nifedipine-induced gingival hyperplasia.

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