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Updated: Aug 15, 2026

Heterotopic Auxiliary Rat Liver Transplantation With Flow-regulated Portal Vein Arterialization in Acute Hepatic Failure
Published on: September 13, 2014
[Albumin-mediated peritoneal dialysis as method of restorational therapy in hepatic insufficiency]
Abstract:
New method of extracorporeal detoxication of organism, which is applied for temporary restoration of hepatic detoxication function in patients with hepatic insufficiency, albumin-mediated peritoneal dialysis, was presented. The main principle of this technology is a transfer through highly permeable dialysis membrane of toxins, which are in affinity with albumin, from the blood to acceptor. The donor's human albumin, circulating in the closed contour, serves as acceptor. The watersoluble lowmolecular substances are excreted according to the concentration gradient. For rapid restoration of acceptoral ability of the donor's albumin solution it was subjected to hemodialysis and carboperfusion. The performance of the procedure guarantees excretion of toxins, combined with albumin, along with excretion of watersoluble toxins.
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