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Updated: Aug 15, 2026
A 3-D Visualization Technique for Bone Remodeling in a Suture Expansion Mouse Model
Published on: August 18, 2023
[A histological study of three-dimensional external zygomatic suture distraction osteogenesis]
En-qun Wang1, Shu-xia Zhou, Yan-pu Liu
1Department of Stomatology, The First Affiliated Hospital, Anhui Medical University, Hefei 230022, China.
Objective:
To explore the histological change in suture of zygomatic bone for the zygomatic suture direct distraction osteogenesis.
Methods:
The zygomatic bone was distracted by 3-D external distraction appliance without osteotomy. The specimens were taken 1, 3, 5 and 8 weeks after, and then examined histologically and compared with the blank contralateral side.
Results:
There were lots of fibroblasts, osteoblasts and capillary vessels in the distracted suture tissues one week after distraction, and the fibers were observed to connect the sides of suture and arranged orderly. The surfaces of the expanded suture were irregular. Bone formation was active in the expanded side. The bone trabeculae were mature and oriented in the direction of distraction in the distracted sides at 3 weeks. A great amount of new woven bones were found in 5-week specimen. New bones were formed completely 8 weeks after the distraction.
Conclusions:
New bone formed rapidly in the distracted side of zygomatic bone under suture distraction osteogenesis without osteotomy.
