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O-Ring Aortic Banding Versus Traditional Transverse Aortic Constriction for Modeling Pressure Overload-Induced Cardiac Hypertrophy
Published on: October 6, 2022
Coarctation of the aorta
1Division of Pediatric Cardiology, The University of Texas/Houston Medical School, 6431 Fannin, MSB 3.130, Houston, TX 77030, USA. P.Syamasundar.Rao@uth.tmc.edu
Insights
Coarctation of the aorta, a congenital heart defect causing hypertension, is treatable. Interventional techniques like balloon angioplasty and stenting are increasingly preferred over surgery for managing this aortic narrowing.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Interventional Cardiology
Background:
- Coarctation of the aorta is a significant congenital heart defect, affecting 5-8% of cases.
- It often presents as secondary hypertension or is detected during routine examinations.
- Key clinical signs include delayed femoral pulses and a significant arm-leg systolic blood pressure difference.
Purpose of the Study:
- To review the diagnosis and management of coarctation of the aorta.
- To highlight the shift towards less invasive, catheter-based interventions.
- To emphasize the need for long-term follow-up data on interventional outcomes.
Main Methods:
- Diagnosis involves echocardiography with Doppler, cardiac catheterization, and angiography.
- Treatment options include surgical repair and transcatheter techniques such as balloon angioplasty and stent implantation.
- The study reviews current trends in managing aortic coarctation.
Main Results:
- Echocardiography and Doppler assess coarctation severity via flow velocities.
- Cardiac catheterization quantifies pressure gradients and angiography visualizes aortic narrowing.
- Transcatheter techniques are gaining prominence due to surgical morbidity.
Conclusions:
- Coarctation of the aorta is a treatable cause of hypertension.
- Transcatheter interventions (angioplasty, stenting) are becoming primary treatment options.
- Further research is needed on the long-term efficacy of these interventional methods.
Abstract:
Coarctation of the aorta is an important, treatable cause of secondary hypertension. Its prevalence varies from 5% to 8% of all congenital heart defects. This condition is most often detected because of a murmur or hypertension found on routine examination. Delayed or absent femoral pulses and an arm/leg systolic blood pressure difference of 20 mm Hg or more in favor of the arms may be considered as evidence for aortic coarctation. The coarctation may be demonstrated on a suprasternal notch two-dimensional echocardiographic view along with increased Doppler flow velocities across the coarctation site. Cardiac catheterization reveals significant systolic pressure gradient (> 20 mm Hg) across the coarctation and angiography demonstrates the degree and type of aortic narrowing. Aortic obstruction may be relieved by surgery or by transcatheter techniques; the latter include balloon angioplasty and stent implantation. In the past, surgery has been used exclusively, but because of morbidity and complications associated with surgery, catheter techniques are increasingly used in the management of aortic coarctation. Balloon angioplasty in children and stents in adolescents and adults are becoming initial therapeutic options for management of coarctation. Studies evaluating long-term follow-up results of the interventional techniques are needed.
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