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Related Experiment Videos

Mild bleeding disorders. A clinical and laboratory study.

J D Parkin1, I L Smith, A I O'Neill

  • 1Haematology Department, Repatriation General Hospital, Heidelberg West, VIC.

The Medical Journal of Australia
|May 4, 1992
PubMed
Summary
This summary is machine-generated.

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In vitro testing revealed abnormal haemostasis in over half of patients with mild bleeding disorders. Easy bruising is a significant indicator of underlying in vitro test abnormalities.

Area of Science:

  • Hematology
  • Clinical Pathology

Background:

  • Mild bleeding disorders present with diverse symptoms.
  • Accurate diagnosis relies on comprehensive in vitro testing.

Purpose of the Study:

  • To evaluate in vitro haemostasis in individuals with symptoms suggestive of mild bleeding disorders.
  • To compare laboratory test results with a healthy reference group.

Main Methods:

  • Prospective study of 93 consecutive patients referred from community and hospital settings.
  • Unselective application of an extensive range of in vitro haemostasis tests.
  • Exclusion of severely ill hospital patients.

Main Results:

  • Abnormal in vitro test results were observed in 53% of subjects.

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  • Prolonged bleeding time occurred in 13%, often with other abnormal tests.
  • Von Willebrand's disease diagnosed in 7% of patients.

    • Conclusions:

    • Abnormal in vitro test results are prevalent in patients with mild bleeding disorder symptoms.
    • Easy bruising is a significant clinical feature associated with abnormal in vitro findings.
    • Comprehensive laboratory evaluation is crucial for diagnosing mild bleeding disorders.