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Related Experiment Videos

Asymptomatic fascioliasis.

Seiji Adachi1, Kazuhiko Kotani, Tetsu Shimizu

  • 1Department of General Internal Medicine, Tottori Central Prefectural Hospital, Japan.

Internal Medicine (Tokyo, Japan)
|November 1, 2005
PubMed
Summary

A 72-year-old man with asymptomatic eosinophilia was diagnosed with human fascioliasis, a liver fluke infection. Laparoscopy confirmed Fasciola hepatica, and treatment led to symptom resolution.

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Area of Science:

  • Medical Parasitology
  • Hepatology
  • Diagnostic Imaging

Background:

  • Human fascioliasis is a neglected tropical disease caused by liver flukes.
  • Zoonotic transmission occurs through ingestion of contaminated water or undercooked vegetation.
  • Asymptomatic cases can be challenging to diagnose, potentially leading to delayed treatment.

Observation:

  • A 72-year-old Japanese man presented with asymptomatic eosinophilia and multiple space-occupying liver lesions on CT scans.
  • Occupational exposure to cattle, serological tests, and imaging suggested zoonotic liver flukes.
  • Immunological examination aided diagnosis, while laparoscopy was essential for confirmation and ruling out malignancy.

Findings:

  • Fasciola hepatica infection was confirmed via laparoscopy and liver biopsy.

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  • The patient received praziquantel treatment.
  • Post-treatment, blood eosinophilia resolved in 4 months, and liver lesions significantly reduced within 12 months.

    • Implications:

    • Laparoscopy with liver biopsy is a critical diagnostic tool for human fascioliasis, especially in asymptomatic presentations.
    • Early diagnosis and treatment of fascioliasis can prevent complications and ensure favorable outcomes.
    • This case highlights the importance of considering zoonotic infections in patients with unexplained liver lesions and eosinophilia.