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Updated: Aug 15, 2026

Establishment of a Modified Ferric Chloride-Induced Superior Sagittal Sinus Thrombosis
Published on: December 30, 2025
Tuberculosis: an uncommon cause of cerebral venous thrombosis?
José Antonio Fiorot Júnior1, André Carvalho Felício, Márcia Mauimi Fukujima
1Division of Neurology, Universidade Federal de São Paulo, São Paulo, SP, Brazil. fiorotjr@terra.com.br
Abstract:
Several infectious etiologies are related to cerebral venous thrombosis (CVT), but a review of literature showed only few cases related to tuberculosis (TB), and only one with neurological manifestations. We report an unusual case of CVT related to TB and mutation in prothrombin gene. A 38-man black presented abrupt right hemiparestesis, and hemiparesis. Investigations revealed CVT. Cerebral spinal fluid (CSF) examination evidenced an infection by Mycobacterium. He was heterozygous for G20210A prothrombin mutation. Probably, hypercoagulability mechanisms of TB, added to mutation of prothrombin gene increase the risk of CVT.
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