Related Experiment Videos

Behçet's disease combined with various types of fistula

Hye Jin Chung1, Bon Cheol Goo, Ju Hee Lee

  • 1Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun- gu, Seoul 120-752, Korea.

Yonsei Medical Journal
|November 1, 2005
PubMed

Insights

Behçet's disease (BD) can cause fistulas, including enterocutaneous and rectovaginal types. Surgical treatment for these fistulas in BD patients often leads to poor outcomes due to disease relapses.

Area of Science:

  • Rheumatology
  • Gastroenterology
  • Vascular Surgery

Background:

  • Behçet's disease (BD) is a multisystem disorder characterized by recurrent ulcers and vasculitis.
  • Severe vasculitis in BD can lead to tissue necrosis and fistula formation.

Purpose of the Study:

  • To present eleven cases of Behçet's disease (BD) associated with various types of fistulas.
  • To analyze the types of fistulas occurring in BD patients and their treatment outcomes.

Main Methods:

  • Case series presentation of eleven patients diagnosed with Behçet's disease and concurrent fistula formation.
  • Documentation of fistula types, including enterocutaneous, rectovaginal, aortoduodenal, urethrovaginal, and urethrocutaneous.

Main Results:

  • Six patients presented with enterocutaneous fistulas, and two with rectovaginal fistulas.
  • Three patients had other fistula types: aortoduodenal, urethrovaginal, and urethrocutaneous.
  • Surgical correction was performed, but frequent relapses resulted in poor prognoses.

Conclusions:

  • Fistula formation is a severe complication of Behçet's disease (BD) vasculitis.
  • Treatment of fistulas in BD patients is challenging, with a high rate of recurrence and poor long-term outcomes.

Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Portal Hypertension01:22

Portal Hypertension

Portal hypertension is an increase in blood pressure within the portal venous system. Normally, this pressure is less than 5 mmHg. It is considered clinically significant when it rises above 10 mmHg. At this threshold, complications from altered blood flow and venous congestion emerge.EtiologyPortal hypertension arises from conditions that impede blood flow through the liver. The most common cause is cirrhosis, in which chronic liver injury leads to fibrotic scarring. This fibrosis narrows or...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...