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[Cardiac tumors].

A Orlandi1, A Ferlosio, C Angeloni

  • 1Istituto di Anatomia ed Istologia Patologica, Università Tor Vergata di Roma, Italia. orlandi@uniroma2.it

Pathologica
|November 2, 2005
PubMed
Summary
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Primary cardiac tumors, including common myxomas, are rare and often diagnosed late due to subtle or absent symptoms. This review details their clinicopathological features and challenges in understanding their origins.

Area of Science:

  • Cardiology
  • Pathology
  • Oncology

Context:

  • Primary cardiac tumors are rare, with benign types comprising about 75% of cases.
  • Cardiac myxomas are the most frequent primary cardiac neoplasm, accounting for approximately 50% of all cases.
  • Accurate subdivision is challenging due to unknown origins and varied presentations.

Purpose:

  • To present the clinicopathological features of main primary cardiac tumors.
  • To highlight the diagnostic challenges associated with cardiac neoplasms.
  • To underscore the ongoing research into the histogenesis of these rare tumors.

Summary:

  • Primary cardiac tumors are classified into benign, malignant, and uncertain aetiology, with sarcomas representing malignant neoplasms.
  • Despite advances in non-invasive imaging like trans-esophageal echocardiography, diagnosis is often delayed due to asymptomatic presentation or non-specific symptoms mimicking other cardiac conditions.

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  • Cardiac myxoma is the most prevalent primary cardiac tumor.

    • Impact:

    • Enhances understanding of rare cardiac tumors for improved clinical diagnosis and management.
    • Identifies gaps in knowledge regarding tumor histogenesis, guiding future research directions.
    • Provides a comprehensive overview for clinicians and researchers in cardiovascular pathology and oncology.