[Correlation between PMI and DNA degradation of costicartilage and dental pulp cells in human being]
Ren Long1, Wei-ping Wang, Ping Xiong
1Department of Forensic Medicine, Nanhua University, Hengyang 421001, China.
Objective:
To probe the correlation between the postmortem interval (PMI) and the DNA degradation of costicartilage and dental pulp cells in human being after death, and to seek a new method for estimating PMI.
Methods:
The image cytometry was used to measure the DNA degradation under different ambient temperatures (30-35 degrees C, 15-20 degrees C) in 0-15 days after death.
Results:
The average DNA content of two kinds of tissue was degradated with the prolongation of PMI. But there was a plateau period of 0-4 days for dental pulp cells of human being in 15-20 degrees C. There was a high negative correlativity P<0.01 between the average DNA content and PMI.
Conclusion:
PMI could be estimated accurately according to the DNA degradation of costicartilage and dental pulp cells in human being after death.
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