The identification of potent and selective imidazole-based inhibitors of B-Raf kinase

Andrew K Takle1, Murray J B Brown, Susannah Davies

  • 1Department of Medicinal Chemistry, Neurology and GI Centre of Excellence for Drug Discovery, GlaxoSmithKline Pharmaceuticals, New Frontiers Science Park, Third Avenue, Harlow, Essex CM19 5AW, UK. Andy.K.Takle@gsk.com