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Goodpasture syndrome in a pregnant woman
D Marie Vasiliou1, Cynthia Maxwell, Prakeshkumar Shah
1Department of Medicine, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.
Background:
Goodpasture syndrome, an immunologic disorder characterized by glomerulonephritis and pulmonary hemorrhage, rarely presents in pregnancy.
Case:
We describe a patient who was diagnosed with Goodpasture syndrome in her second trimester. She required daily hemodialysis, intermittent plasmapheresis, and immunosuppressive therapy. Her pregnancy was complicated by hypertension, and she delivered a low birth weight neonate prematurely at 26 4/7 weeks of gestation by cesarean due to nonreassuring fetal status. Deterioration in the fetal status may have been secondary to complications of hypertension, in addition to prematurity.
Conclusion:
Goodpasture syndrome in pregnancy may be associated with significant maternal and fetal morbidity.
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