Related Experiment Video
Updated: Aug 15, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
Structural brain correlates of unconstrained motor activity in people with schizophrenia
Tom F D Farrow1, Michael D Hunter, Iain D Wilkinson
1Sheffield Cognition and Neuroimaging Laboratory (SCANLab), Department of Academic Clinical Psychiatry, University of Sheffield,The Longley Centre, Northern General Hospital, Norwood Grange Drive, Sheffield S5 7JT,UK. t.f.farrow@sheffield.ac.uk
Abstract:
Avolition affects quality of life in chronic schizophrenia. We investigated the relationship between unconstrained motor activity and the volume of key executive brain regions in 16 male patients with schizophrenia. Wristworn actigraphy monitors were used to record motor activity over a 20 h period. Structural magnetic resonance imaging brain scans were parcellated and individual volumes for anterior cingulate cortex and dorsolateral prefrontal cortex extracted. Patients'total activity was positively correlated with volume of left anterior cingulate cortex. These data suggest that the volume of specific executive structures may affect (quantifiable) motor behaviours, having further implications for models of the 'will' and avolition.
More Related Videos
11:31Functional Near Infrared Spectroscopy of the Sensory and Motor Brain Regions with Simultaneous Kinematic and EMG Monitoring During Motor Tasks
Published on: December 5, 2014
05:25An Experiment Using Functional Near-Infrared Spectroscopy and Robot-Assisted Multi-Joint Pointing Movements of the Lower Limb
Published on: June 7, 2024
Related Concept Videos
Positive Symptoms of Schizophrenia: Hallucinations and Delusions
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...
Biological Causes of Schizophrenia
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.