Related Experiment Video
Updated: Jul 30, 2026

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
Published on: August 15, 2019
Familial Dandy-Walker syndrome: a case report supporting an autosomal inheritance
Thomas W H Bragg1, Edward J St George, Guy A Wynne-Jones
1Department of Neurosurgery, Diana Princess of Wales Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK. twhbragg@hotmail.com
Introduction:
We report an isolated pedigree in which a consanguineous couple had twin sons with Dandy-Walker malformation (DWM). The mother is similarly affected with the disorder.
Discussion:
DWM is an abnormality of the central nervous system, which leads to hydrocephalus and is associated with other abnormalities.
Conclusion:
Inheritance of the disorder remains controversial, with the majority perceived to be sporadic cases. This report suggests an autosomal inheritance.
Related Concept Videos
Genetic Lingo
Pedigree Analysis
Sex-linked Disorders
Genomic Imprinting and Inheritance
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Incomplete Dominance
Huntington Disease l: Introduction

