Epidemiological aspects of rotavirus infection in Ahwaz, Iran

Alireza Samarbafzadeh1, Elham Mazaheri Tehrani, Manouchehr Makvandi

  • 1Department of Virology, Ahwaz University of Medical Sciences, Ahwaz, Iran.

Insights

Rotavirus infection is common in children in Ahwaz, Iran, affecting 29.5% of those studied. The highest rates were observed in children aged 7-12 months, indicating a significant age-related risk for rotavirus gastroenteritis.

Area of Science:

  • Virology
  • Pediatrics
  • Public Health

Background:

  • Rotavirus is a leading cause of severe diarrhea in children globally.
  • Understanding regional rotavirus prevalence is crucial for public health interventions.

Purpose of the Study:

  • To determine the prevalence and characteristics of rotavirus infections in children in Ahwaz, Iran.
  • To analyze the relationship between age and rotavirus infection rates.

Main Methods:

  • Stool samples were collected from 200 children (aged 1-24 months) in Ahwaz.
  • Polyacrylamide gel electrophoresis (PAGE) was used for rotavirus isolation and characterization.
  • Samples were analyzed from both inpatient and outpatient settings.

Main Results:

  • Rotavirus was detected in 29.5% of the children studied.
  • Infection rates were higher in inpatients (36.5%) compared to outpatients (26.3%).
  • The highest prevalence was observed in children aged 7-12 months (statistically significant, p < 0.05).
  • The long (L) electrophoretype (78%) was predominant, followed by the short (S) electrophoretype (20.3%).

Conclusions:

  • Rotavirus infection is a significant cause of childhood diarrhea in Ahwaz, Iran.
  • Age is a critical factor in rotavirus infection rates among young children.
  • Further epidemiological studies across Iran are needed to inform prevention strategies.

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