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Published on: July 11, 2012
Bromine is an endogenous component of a vanadium bromoperoxidase
Martin C Feiters1, Catherine Leblanc, Frithjof C Küpper
1Department of Organic Chemistry, Institute of Molecules and Materials (IMM), Radboud University Nijmegen, 1 Toernooiveld, NL-6525 ED Nijmegen, The Netherlands.
Abstract:
On the basis of EXAFS and MS/MS experimental results and a reinterpretation of the electron density map obtained by X-ray crystallography, we describe a new post-translational modification, that is, a 3,5-dibromotyrosine residue that is incorporated in the polypeptide chain of a vanadium haloperoxidase.
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