Related Experiment Video

Updated: Aug 15, 2026

Models of Bone Metastasis
08:49

Models of Bone Metastasis

Published on: September 4, 2012

How can bone turnover markers be best utilized for prediction of skeletal events in patients with solid tumors?

Gregory R Mundy1

  • 1University of Texas Health Science Center at San Antonio, Department of Cellular and Structural Biology, TX 78229-3900, USA. mundy@uthscsa.edu

Nature Clinical Practice. Oncology
|November 3, 2005
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

Development of a Human Preclinical Model of Osteoclastogenesis from Peripheral Blood Monocytes Co-cultured with Breast Cancer Cell Lines
06:00

Development of a Human Preclinical Model of Osteoclastogenesis from Peripheral Blood Monocytes Co-cultured with Breast Cancer Cell Lines

Published on: September 13, 2017

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
07:17

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation

Published on: April 14, 2016

Related Experiment Videos

Last Updated: Aug 15, 2026

Models of Bone Metastasis
08:49

Models of Bone Metastasis

Published on: September 4, 2012

Development of a Human Preclinical Model of Osteoclastogenesis from Peripheral Blood Monocytes Co-cultured with Breast Cancer Cell Lines
06:00

Development of a Human Preclinical Model of Osteoclastogenesis from Peripheral Blood Monocytes Co-cultured with Breast Cancer Cell Lines

Published on: September 13, 2017

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
07:17

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation

Published on: April 14, 2016

Related Concept Videos

Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...

Articles linked to this work by shared authors, journal, and citation graph.

The polyphenol resveratrol promotes skeletal growth in mice through a sirtuin 1-bone morphogenic protein 2 longevity axis.

British journal of pharmacology·2018

Bmp2 in osteoblasts of periosteum and trabecular bone links bone formation to vascularization and mesenchymal stem cells.

Journal of cell science·2013

Osteoclasts in multiple myeloma are derived from Gr-1+CD11b+myeloid-derived suppressor cells.

PloS one·2012

Silent information regulator (Sir)T1 inhibits NF-κB signaling to maintain normal skeletal remodeling.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2012

Bone-derived IGF mediates crosstalk between bone and breast cancer cells in bony metastases.

Cancer research·2012

Bone marrow stromal cells create a permissive microenvironment for myeloma development: a new stromal role for Wnt inhibitor Dkk1.

Cancer research·2012

Effect of bisphosphonates on pain and quality of life in patients with bone metastases.

Nature clinical practice. Oncology·2009

Treatment of advanced disease in patients with well-differentiated neuroendocrine tumors.

Nature clinical practice. Oncology·2009

Cetuximab therapy for patients with advanced squamous cell carcinomas of the head and neck.

Nature clinical practice. Oncology·2009

Pharmacogenomic progress in individualized dosing of key drugs for cancer patients.

Nature clinical practice. Oncology·2009

Xoft Axxent electronic brachytherapy: a new device for delivering brachytherapy to the breast.

Nature clinical practice. Oncology·2009

Unintended pregnancy during radiotherapy for cancer.

Nature clinical practice. Oncology·2009
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us