Early monoaminergic dysfunction
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Y Takeuchi1, T Sawada, P Jenner
1Department of Pediatrics, Kyoto Prefectural University of Medicine, Japan.
Brain & Development
|May 1, 1992
Abstract:
The chemical anatomy of the Rett syndrome and experimental studies concerning early monoaminergic lesions were overviewed. An early monoaminergic dysfunction is a likely occurrence for the mechanism underlying the Rett syndrome. For assessing the alteration of monoamine neuron system, 1) regional vulnerability, 2) age-dependent vulnerability and 3) interaction between the monoamine neuron systems should be considered.