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Published on: December 3, 2021
[Comparable analysis of in-hospital mortality in patients with acute myocardial infarction]
Mei Zhang1, Ti-gang Huang, Guang-ping Li
1Department of Cardiology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China. chyouyou@126.com
Objective:
To investigate the change of the mortality of AMI and influence factors within 20 years.
Methods:
Clinic data of 134 AMI patients from 1980 to 1983, 354 AMI patients from 1990 to 1993 and 817 AMI patients from 2000 to 2003 were comparably analyzed.
Results:
In hospital mortality of AMI was 22.4% from 1980 to 1983, 14.4% from 1990 to 1993 and 9.2% from 2000 to 2003, respectively (P < 0.01). The decrease of in-hospital mortality in male was more significant than in female (P < 0.01). The corresponding factors for decrease of mortality were younger than 60 years old, first onset of AMI, successful rescue of cardiac arrest and reperfusion management of infarction relative artery. The disadvantage factor was female.
Conclusions:
Improvement of medical and reperfusion management of AMI conduced in significant decreases of hospital mortality.
Insights
Mortality from acute myocardial infarction (AMI) significantly decreased over 20 years due to improved medical care and reperfusion strategies. Factors like younger age and male sex were associated with better outcomes.
Area of Science:
- Cardiology
- Public Health
Context:
- Acute myocardial infarction (AMI) remains a leading cause of mortality worldwide.
- Significant advancements in medical treatment and emergency response protocols have occurred over the past few decades.
Purpose:
- To analyze trends in in-hospital mortality rates for AMI patients over a 20-year period.
- To identify key factors influencing changes in AMI mortality.
Summary:
- In-hospital mortality for AMI decreased from 22.4% (1980-1983) to 9.2% (2000-2003).
- Factors contributing to reduced mortality included younger age (<60), first-time AMI, successful cardiac arrest resuscitation, and timely reperfusion therapy.
- Male patients showed a more significant mortality reduction compared to female patients, highlighting a potential gender disparity in outcomes.
Impact:
- Improved medical management and reperfusion therapies have substantially reduced hospital mortality for AMI.
- Findings underscore the importance of timely interventions and suggest areas for targeted improvements in patient care, particularly for female patients.
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