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[New trends in pediatric endocarditis]

A Carceller1, M H Lebel, G Larose

  • 1Servicio de Pediatría, Departamento de Pediatría, CHU Sainte-Justine, Université de Montréal, Québec, Canadá. ana_carceller@ssss.gouv.qc.ca

Anales De Pediatria (Barcelona, Spain : 2003)
|November 4, 2005
PubMed

Insights

Pediatric endocarditis incidence increased, with higher risks for children with central catheters or immunodeficiency. However, significant reductions in morbidity and mortality were observed between 1960-1985 and 1986-2000.

Area of Science:

  • Pediatric Cardiology
  • Infectious Diseases
  • Epidemiology

Context:

  • Endocarditis in children presents unique challenges, often linked to congenital heart disease or invasive procedures.
  • Understanding trends in pediatric endocarditis is crucial for effective management and prevention strategies.

Purpose:

  • To evaluate the epidemiology, etiology, and outcomes of infective endocarditis in pediatric patients.
  • To compare recent trends (1986-2000) with historical data (1960-1985) to identify changes in incidence, risk factors, and outcomes.

Summary:

  • A cohort study of 56 pediatric patients (1986-2000) revealed an increased incidence of endocarditis compared to 1960-1985.
  • Congenital heart disease was the most common underlying condition. Streptococci and Staphylococci were the primary pathogens. Central catheters and vascular prostheses were noted risk factors.
  • Morbidity decreased from 85.7% to 46.4%, and mortality decreased from 27% to 12.5% over the study periods.

Impact:

  • The study highlights an increased risk of endocarditis in children with central catheters and underlying immunodeficiency.
  • Healthy children with endocarditis face a higher risk of complications.
  • Significant improvements in morbidity and mortality underscore advancements in pediatric endocarditis care.
Abstract

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