Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hyperkalaemic periodic paralysis and anaesthesia.

E M Ashwood1, W J Russell, D D Burrow

  • 1Department of Anaesthesia and Intensive Care, Royal Adelaide Hospital, North Terrace.

Anaesthesia
|July 1, 1992
PubMed
Summary

Hyperkalaemic periodic paralysis, a rare condition, can be safely managed during anesthesia. Careful pre-operative potassium management and avoiding specific anesthetic agents prevent paralytic episodes in affected patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anaphylaxis to muscle relaxants: an audit of ten years of allergy testing at the Royal Adelaide Hospital.

Anaesthesia and intensive care·2012
Same author

Hypoxaemia associated with one-lung anaesthesia: an alternative approach.

British journal of anaesthesia·2011
Same author

Anaphylaxis to patent blue dye--the benefit and the risk.

Anaesthesia and intensive care·2011
Same author

Speeding dantrolene preparation for treating malignant hyperthermia.

Anaesthesia and intensive care·2011
Same author

Persistent allergy to suxamethonium 39 years after exposure.

Anaesthesia and intensive care·2011
Same author

An audit of residual neuromuscular block in Australasia.

Anaesthesia and intensive care·2010

Area of Science:

  • Neurology
  • Anesthesiology
  • Genetics

Background:

  • Hyperkalaemic periodic paralysis (HPP) is a rare inherited disorder characterized by episodes of muscle weakness or paralysis due to elevated serum potassium levels.
  • It is often associated with myotonia, a condition causing delayed muscle relaxation.
  • Understanding the anesthetic implications for HPP patients is crucial for safe surgical management.

Observation:

  • This report details the anesthetic management of four members of a family diagnosed with hyperkalaemic periodic paralysis and paramyotonia.
  • Previous anesthetic experiences in three family members resulted in paralytic episodes.
  • The current anesthetic approach successfully avoided these complications.

Findings:

  • The study highlights successful anesthetic management in HPP patients by implementing specific strategies.

Related Experiment Videos

  • Key strategies include pre-operative potassium depletion, prevention of carbohydrate depletion, avoidance of potassium-releasing anesthetic drugs, and maintenance of normothermia.
  • No abnormal sensitivity to nondepolarizing neuromuscular relaxants was observed in these patients.

    • Implications:

    • Patients with hyperkalaemic periodic paralysis can undergo anesthesia without complications when appropriate precautions are taken.
    • This approach provides a guideline for anesthesiologists managing patients with HPP.
    • Further research may explore the precise mechanisms of neuromuscular relaxant interactions in HPP.