Related Experiment Videos
Delayed hypersensitivity to diltiazem in two patients
A Romano1, F Pietrantonio, A Garcovich
1Istituto di Clinica Medica, Università Cattolica del S. Cuore, Rome, Italy.
Annals of Allergy
|July 1, 1992
Abstract:
We report two cases of cutaneous adverse reactions during treatment with diltiazem. Both patients developed wide-spread, pruriginous, erythematous, maculopapular eruptions with fever and facial angioedema, 48 to 72 hours after starting diltiazem. Delayed hypersensitivity to diltiazem was suspected and the diagnosis was confirmed by skin patch tests followed by cutaneous biopsy.