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Published on: March 25, 2016
Cytomegalovirus-induced interstitial pneumonitis in a patient with dermatomyositis
Timuçin Kaşifoğlu1, Cengiz Korkmaz, Ragip Ozkan
1Division of Rheumatology, Department of Internal Medicine, Eskişehir Osmangazi University Medical Faculty, Eskişehir, Turkey.
Abstract:
Dermatomyositis (DM) patients might present with pulmonary involvement as the first manifestation or during the follow-up period. It is sometimes difficult to determine whether the clinical manifestations related with pulmonary involvement are due to DM or to an infectious process. We report a case of DM patient who developed interstitial pneumonitis induced by cytomegalovirus (CMV) while receiving immunosuppressive treatment. To the best of our knowledge, this is the second report in the literature of interstitial pneumonitis secondary to CMV infection in a patient with DM.
Insights
Dermatomyositis patients can develop lung issues. This case highlights cytomegalovirus-induced interstitial pneumonitis in a dermatomyositis patient on immunosuppressants.
Area of Science:
- Pulmonology
- Rheumatology
- Infectious Diseases
Background:
- Pulmonary involvement is a known complication of dermatomyositis (DM).
- Differentiating DM-related lung issues from infections can be challenging.
- Immunosuppressive therapy in DM increases susceptibility to opportunistic infections.
Observation:
- A dermatomyositis patient developed interstitial pneumonitis.
- The pneumonitis occurred during immunosuppressive treatment.
- Cytomegalovirus (CMV) was identified as the causative agent.
Findings:
- The interstitial pneumonitis was directly induced by cytomegalovirus (CMV) infection.
- This represents a rare instance of CMV-induced lung disease in a dermatomyositis patient.
- The case underscores the diagnostic difficulty in distinguishing DM-related pulmonary manifestations from infections.
Implications:
- Highlights the importance of considering opportunistic infections like CMV in DM patients with pulmonary symptoms.
- Suggests vigilant monitoring for infections in DM patients undergoing immunosuppressive therapy.
- Contributes to the limited literature on CMV-induced interstitial pneumonitis in dermatomyositis, aiding future diagnosis and management.
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