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Updated: Aug 15, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
[Acute renal failure, hemolysis and thrombocytopenia]
D Rossi1, D Ricciardi, M Gaburri
1Struttura Complessa di Nefrologia e Dialisi, Ospedale R. Silvestrini, Azienda Ospedaliera di Perugia, S. Andrea delle Fratte, 06100 Perugia, Italy. rossidav72@virgilio.it
Abstract:
A 41-year-old male was admitted because of severe systemic hypertension and acute renal failure (ARF) that required hemodialysis (HD). Also present were hemolytic anemia, thrombocytopenia and increased plasmatic levels of aldosterone and reninic activity. The diagnostic tests performed during the recovery led to the conclusion of malignant hypertension. This case dealt with a cause of ARF, which is not currently so common; physicians should be aware of this condition especially when it is present with hemolytic anemia and thrombocytopenia, which are the microangiopathy markers.
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