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Updated: Aug 15, 2026

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
Locked pi-expanded chlorins in two steps from simple tetraarylporphyrins
Julien Fouchet1, Christophe Jeandon, Romain Ruppert
1U.M.R. 7177 du C.N.R.S., Faculté de Chimie, Université Louis Pasteur, 1, Rue Blaise Pascal, F-67000 Strasbourg, France.
Abstract:
[reaction: see text] Upon tandem Reformatsky reaction, easily accessible porphyrinic ketones give "locked" chlorinic diester. Both ketones and diesters, as bases or palladium complexes, efficiently generate singlet dioxygen, as demonstrated by trapping with cholesterol.
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