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Synthesis of the C6-C21 segment of amphidinolide E

James A Marshall1, Gregory Schaaf, Andrew Nolting

  • 1Department of Chemistry, University of Virginia, P.O. Box 400319, Charlottesville, Virginia 22904, USA. jam5x@virginia.edu

Organic Letters
|November 5, 2005
PubMed

Abstract:

[reaction: see text] A convergent approach to a C6-C21 segment of the polyketide amphidinolide E has been developed through combination of three subunits by allenylindium bromide-aldehyde addition and Suzuki sp2-sp3 coupling.

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