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Synthesis of the C6-C21 segment of amphidinolide E
James A Marshall1, Gregory Schaaf, Andrew Nolting
1Department of Chemistry, University of Virginia, P.O. Box 400319, Charlottesville, Virginia 22904, USA. jam5x@virginia.edu
Abstract:
[reaction: see text] A convergent approach to a C6-C21 segment of the polyketide amphidinolide E has been developed through combination of three subunits by allenylindium bromide-aldehyde addition and Suzuki sp2-sp3 coupling.
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