In vivo assessment of emphysema in mice by high resolution X-ray microtomography
A A Postnov1, K Meurrens, H Weiler
1Department of Biomedical Sciences, Univeristy of Antwerp, Belgium.
Journal of Microscopy
|November 5, 2005
Abstract:
High resolution X-ray microtomography (micro-CT) was used for the detection of emphysema in live mice. Emphysema was induced in C57BL/6 J mice by intratracheal instillation of different amounts of porcine pancreatic elastase. This emphysema could be clearly detected by micro-CT seven weeks post-treatment: analysis of the whole data set of virtual cross-sections showed the presence of a dose-dependent level of emphysema.
