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Cutaneous oxalosis after long-term hemodialysis
J G Abuelo1, S T Schwartz, A J Reginato
1Division of Renal Diseases, Rhode Island Hospital, Brown University, Providence, RI 02902.
Archives of Internal Medicine
|July 1, 1992
Summary
Dialysis patients can develop skin calcifications due to calcium oxalate deposits. This case highlights potential contributing factors like vitamin C and tea intake in long-term hemodialysis patients.
Area of Science:
- Nephrology
- Dermatology
- Mineral Metabolism
Background:
- Long-term hemodialysis is a treatment for end-stage renal disease.
- Cutaneous calcifications are a rare complication in dialysis patients.
- Dialysis oxalosis involves oxalate deposition in tissues.
Observation:
- A 27-year-old woman on long-term hemodialysis presented with finger calcifications.
- Skin biopsy confirmed calcium oxalate deposits.
Findings:
- This case presents pathological and crystallographic findings of skin calcifications in dialysis oxalosis.
- Potential contributing factors identified include vitamin C supplements, high tea consumption, elevated serum ionized calcium, and prolonged hemodialysis duration.
Implications:
- Understanding the etiology of dialysis oxalosis is crucial for patient management.
- Further research may elucidate the precise mechanisms and preventative strategies for cutaneous calcifications in hemodialysis patients.
- This case underscores the importance of monitoring mineral metabolism and potential iatrogenic contributions in chronic kidney disease patients.
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