Related Experiment Videos

[Clinical risk factors for deep vein thrombosis after total hip and knee arthroplasty]

Zhen-peng Guan1, Hou-shan Lü, Yan-zhang Chen

  • 1Arthritis Institute, Peking University People's Hospital, Beijing 100044, China. guan_zhenpeng@sina.com

Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]
|November 8, 2005
PubMed

Insights

Female sex, obesity, and cement use increase deep vein thrombosis (DVT) risk after hip and knee replacement. Rheumatoid arthritis diagnosis appears protective against DVT in these patients.

Area of Science:

  • Orthopedic Surgery
  • Vascular Medicine
  • Clinical Risk Factor Analysis

Context:

  • Deep vein thrombosis (DVT) is a significant complication following major orthopedic procedures like total hip arthroplasty (THA) and total knee arthroplasty (TKA).
  • Prophylactic anticoagulation is standard, yet DVT incidence remains a concern, particularly in specific patient populations.
  • Identifying precise clinical risk factors is crucial for refining preventative strategies in Chinese patients undergoing THA/TKA.

Purpose:

  • To investigate clinical risk factors associated with DVT development in Chinese patients undergoing THA and TKA.
  • To analyze the impact of pre-operative and post-operative clinical factors on DVT incidence despite prophylactic treatment.
  • To identify both risk and protective factors for DVT in this specific surgical context.

Summary:

  • This study analyzed 128 THA/TKA procedures in 95 Chinese patients receiving low-molecular-weight heparin prophylaxis.
  • Color Doppler ultrasonography detected DVT in 47.4% of patients; proximal DVT was 3.2%.
  • Logistic regression identified female sex (OR 10.008), obesity (OR 3.094), and cement usage (OR 8.887) as significant risk factors, while diagnosed rheumatoid arthritis (RA) was a protective factor (OR 0.194).

Impact:

  • Findings highlight specific demographic and procedural factors (female sex, obesity, cement use) that elevate DVT risk post-THA/TKA.
  • The protective role of rheumatoid arthritis warrants further investigation for potential therapeutic insights.
  • Results can inform targeted DVT prevention strategies and risk stratification for orthopedic surgery patients in China.
Abstract

Related Concept Videos

Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...