Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hearing

Hearing

When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Structural and functional mapping of protective human monoclonal antibodies against enterovirus A71.

Science advances·2026

Same author

Author Correction: Production of an immunogenic trivalent poliovirus virus-like particle vaccine candidate in yeast using controlled fermentation.

NPJ vaccines·2026

Same author

Cattle antibodies identify a cross-serotype broadly neutralising foot-and-mouth disease virus epitope.

NPJ vaccines·2026

Same author

The low-density lipoprotein receptor LDLR mediates cellular entry of nonenveloped hepatitis A virus.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

Amino acid and viral binding by the high-affinity Cationic Amino acid Transporter 1 (CAT1) from Mus musculus.

Nature communications·2026

Same author

Capsid restructuring activates semi-conservative dsRNA transcription in cystovirus ɸ6.

Molecular cell·2026

Same journal

Tomogram exploration through template matching and deep learning.

Current opinion in structural biology·2026

Same journal

A comparative review of cryo-electron ptychography: Biological applications and future perspectives.

Current opinion in structural biology·2026

Same journal

Metabolic disruptions through a three-dimensional genomic lens.

Current opinion in structural biology·2026

Same journal

Collective variable design for biomolecular conformational dynamics.

Current opinion in structural biology·2026

Same journal

Polymer scaling in protein crowding: From dilute coils to semidilute meshes.

Current opinion in structural biology·2026

Same journal

Tuning the physicochemical properties of rationally designed protein-based biomolecular condensates.

Current opinion in structural biology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 25, 2026

Accuracy in Dental Medicine, A New Way to Measure Trueness and Precision

Accuracy in Dental Medicine, A New Way to Measure Trueness and Precision

Published on: April 29, 2014

What does structure tell us about virus evolution?

Dennis H Bamford¹, Jonathan M Grimes, David I Stuart

¹Institute of Biotechnology, and Department of Biological and Environmental Sciences, University of Helsinki, PO Box 56, 00014 Helsinki, Finland.

Current Opinion in Structural Biology

|November 8, 2005

Summary

This summary is machine-generated.

Recent studies reveal that viruses infecting diverse hosts like bacteria and humans share structural similarities. This suggests a common origin for viruses across different life domains, challenging previous biological assumptions.

More Related Videos

A Standardized Approach to Extra-Oral and Intra-Oral Digital Photography

A Standardized Approach to Extra-Oral and Intra-Oral Digital Photography

Published on: July 22, 2022

Semi-Automated Planimetric Quantification of Dental Plaque Using an Intraoral Fluorescence Camera

Semi-Automated Planimetric Quantification of Dental Plaque Using an Intraoral Fluorescence Camera

Published on: January 27, 2023

Related Experiment Videos

Last Updated: May 25, 2026

Accuracy in Dental Medicine, A New Way to Measure Trueness and Precision

Accuracy in Dental Medicine, A New Way to Measure Trueness and Precision

Published on: April 29, 2014

A Standardized Approach to Extra-Oral and Intra-Oral Digital Photography

A Standardized Approach to Extra-Oral and Intra-Oral Digital Photography

Published on: July 22, 2022

Semi-Automated Planimetric Quantification of Dental Plaque Using an Intraoral Fluorescence Camera

Semi-Automated Planimetric Quantification of Dental Plaque Using an Intraoral Fluorescence Camera

Published on: January 27, 2023

Area of Science:

Virology
Evolutionary Biology
Structural Biology

Background:

Viruses are the most abundant life forms, causing significant human suffering and economic loss.
The origins and organization of the virosphere remain largely unknown.
Previously, viruses infecting evolutionarily distant hosts were considered distinct.

Purpose of the Study:

To investigate the origins of viruses.
To explore potential commonalities between viruses infecting hosts from different domains of life (bacteria, archaea, and eukarya).

Main Methods:

Structural analyses of virion architecture.
Comparative analysis of viral coat protein topology.

Main Results:

Unexpected similarities in virion architecture and coat protein topology were identified.
These similarities are not apparent through sequence comparisons alone.
Evidence suggests a shared evolutionary origin for viruses infecting evolutionarily distant hosts.

Conclusions:

The study challenges the notion that viruses infecting bacteria and humans are entirely distinct.
Structural data indicates a common ancestry for viruses across different domains of life.
This finding provides new insights into the organization and evolution of the global virosphere.