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Updated: Aug 15, 2026

Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants
Published on: February 21, 2015
An 8q21 deletion in a patient with comorbid psychosis and mental retardation
Nora Urraca1, Maria de la Luz Arenas-Sordo, Abigail Ortiz-Dominguez
1Laboratorio de Genética Psiquiátrica, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calzada México-Xochimilco 101, col San Lorenzo Huipulco c.p. 14370, México City, México. urracanora@yahoo.com
Abstract:
Systematic investigations indicate that some of the recognized psychiatric disorders can be identified among those with mental retardation due to chromosomal abnormalities. We report a psychotic patient with mild mental retardation (intelligence quotient: 68) and minor anomalies that had a chromosomal aberration not previously described in a psychotic patient. Our patient highlights the importance of the cytogenetic study in psychiatric patients with comorbid mental retardation or minor anomalies. In addition, her psychosis symptoms may be helpful to propose a new candidate gene for psychosis.
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