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[Glucocorticosteroids in the treatment of subglottic laryngitis in children]
1Oddział Otolaryngologiczny, SZPZOZ im. Prof. J. Bogdanowicza w Warszawie.
Insights
Subglottic laryngitis, a severe childhood illness, involves sudden breathing difficulties. Nebulized budesonide offers a safe and effective treatment option for children with moderate to severe cases.
Area of Science:
- Pediatric Pulmonology
- Emergency Medicine
- Pharmacology
Context:
- Subglottic laryngitis is an acute pediatric respiratory emergency characterized by rapid onset of subglottic edema.
- Symptoms include barking cough, stridor, inspiratory dyspnea, and potential for severe respiratory distress.
- This condition can be life-threatening in young children.
Purpose:
- To evaluate the efficacy of nebulized glucocorticoids, specifically budesonide, in treating subglottic laryngitis in children.
- To assess the safety and effectiveness of budesonide nebulization for moderate to severe cases.
Summary:
- A study involving 169 children (9 months to 5 years) with subglottic laryngitis assessed treatment outcomes.
- Patients received nebulized budesonide, and disease severity was evaluated using a clinical croup score.
- Results demonstrated that nebulized budesonide is a safe and effective treatment for moderate to severe subglottic laryngitis.
Impact:
- Nebulized budesonide provides a safe and effective therapeutic option for pediatric subglottic laryngitis.
- This treatment can potentially reduce the severity and duration of respiratory distress in affected children.
- Findings support the use of budesonide as a key intervention in managing this acute pediatric condition.
Abstract:
Subglottic laryngitis is one of the acute children's diseases, directly caused by a violently growing edema of the subglottic area. Its symptoms generally appear very suddenly, when children seem to be in perfect health, at night, several hours after falling asleep. Their symptoms included barking cough, clear voice, stridor, inspiratory dyspnoea with participation of auxiliary respiratory muscles, excitation and anxiety of a child, changes in skin coloration. The movement of the wings of the nostrils is intensified. In especially severe cases, agitation, cyanosis, pallor of skin, obnubilation, apnea, loss of consciousness and circulatory failure may also occur. Subglottic laryngitis is a disease, which can threaten the life of a small child. The aim of this study was to observe efficacy of the treatment of the subglottic laryngitis with glucocorticoids, especially budesonide in nebulization. The research covered 169 children: 58 girls (34.31%) and 111 boys (65.69%) aged 9. months do 5. years (mean 3 years 6 months) hospitalized in the Children's Hospital in Warsaw with the following symptoms: dry barking cough, stridor, inspiratory dyspnoea with the participation of auxiliary respiratory muscles, agitation and change of colour of skin. The examination of each patient included subjective, objective (pediatric and laryngological). Disease severity was assessed by a clinical croup score based on stridor, cough retractions, dyspnoea and cyanosis and the overall clinical assessment was scored on a visual scale. The results indicate that nebulised budesonide can be used as a safe and effective alternative treatment in children with moderate to severe subglottic laryngitis.
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