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Updated: Aug 15, 2026
Germ Cell Transplantation and Testis Tissue Xenografting in Mice
Published on: February 6, 2012
Births using sperm retrieved via immediate microdissection of a solitary testis with cancer
Benjamin B Choi1, Marc Goldstein, Maureen Moomjy
1Department of Urology, New York Presbyterian Hospital-Weill Medical College of Cornell University, New York, New York, USA.
Objective:
To determine the feasibility of achieving births using sperm retrieved from a solitary testis with cancer.
Design:
Prospective clinical study of azoospermic men with testis cancer in a solitary testis.
Setting:
Infertility patients in an academic environment.
Patient(S):
Azoospermic men with previous history of orchiectomy and testis cancer in a remaining solitary testis.
Intervention(S):
Viable sperm were retrieved by immediate microdissection of paratumor testicular tissue from orchiectomy specimen.
Main Outcome Measure(S):
Live births were achieved using sperm from immediate microdissection of orchiectomy specimen with testis cancer.
Conclusion(S):
Azoospermic men with cancer in a solitary testis have potential for fertility.
