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Liver transplantation in children: part 1--peri-operative issues
Rachel M Taylor1, Linda S Franck, Faith Gibson
1Paediatric Liver Centre, King's College Hospital, London, Centre for Nursing and Allied Health Professions Research, Institute of Child Health, London, Florence Nightingale School of Nursing and Midwifery, King's College London. rachel.m.taylor@kcl.ac.uk
Insights
This review summarizes paediatric liver transplantation, covering surgical issues, complications from surgery and immunosuppression, and the emotional impact on children and families. Enhanced knowledge among healthcare professionals is crucial for improved patient outcomes.
Area of Science:
- Pediatric Gastroenterology and Hepatology
- Transplant Surgery
- Immunology
Background:
- Paediatric liver transplantation is a complex procedure with significant implications.
- Understanding peri-operative issues, indications, and methods is vital.
- Post-transplant care involves managing complications and immunosuppression.
Purpose of the Study:
- To provide a comprehensive review of clinical and research literature on paediatric liver transplantation.
- To outline peri-operative considerations and historical context.
- To discuss complications and long-term health implications.
Main Methods:
- Literature review of clinical and research studies.
- Summary of historical data and transplantation techniques.
- Analysis of surgical and immunosuppression-related complications.
Main Results:
- Paediatric liver transplantation involves intricate peri-operative management.
- Complications can arise from surgery and long-term immunosuppression.
- Prolonged hospital stays and emotional impact on patients and families are significant.
Conclusions:
- Healthcare professionals require enhanced knowledge of paediatric liver transplantation.
- Addressing surgical and immunosuppression complications is key to improving outcomes.
- Long-term health implications and psychosocial support are critical aspects of care.
Abstract:
This two-part review provides a comprehensive summary of clinical and research literature on paediatric liver transplantation. Part 1 outlines the peri-operative issues of liver transplantation, covers a brief history, discusses the indications and methods of transplantation and outlines the physical complications which can occur either as a result of the surgery or the subsequent immunosuppressive therapy required to maintain graft integrity. Post-liver transplantation care may require prolonged admission in hospital due to the complications that can occur during surgery and as a result of immunosuppression. This can have a further impact on the emotional status of the child and family. Health care professionals in all settings require greater knowledge about paediatric liver transplantation, its associated complications and long-term health implications.
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