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The gift that keeps on giving.

Steven D Burdette1, Jack M Bernstein

  • 1Division of Infectious Disease, Department of Medicine, Wright State University School of Medicine, Dayton, OH 45428, USA.

Skinmed
|November 9, 2005
PubMed
Summary
This summary is machine-generated.

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Recurrent lower extremity infections, like cellulitis, can be managed with targeted antibiotic therapy. Prophylactic antibiotics may reduce the frequency of these debilitating infections in at-risk patients.

Area of Science:

  • Infectious Diseases
  • Dermatology

Background:

  • Chronic lower extremity lymphedema and stasis dermatitis are associated with an increased risk of recurrent infections.
  • Cellulitis is a common bacterial skin infection that can lead to significant morbidity.

Observation:

  • Two cases of recurrent lower extremity infections are presented.
  • Case 1 involved a 39-year-old man with lymphedema experiencing recurrent cellulitis.
  • Case 2 involved a 52-year-old obese man with stasis dermatitis and a history of recurrent cellulitis.

Findings:

  • Both patients presented with acute symptoms of lower extremity infection, including pain, swelling, and erythema.
  • Intravenous antibiotics (clindamycin, cefazolin) led to clinical improvement in both cases.
  • Suppressive antibiotic therapy was utilized for long-term management in both patients, with one patient on a regimen for over a decade.

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Implications:

  • These cases highlight the importance of appropriate antibiotic management for recurrent lower extremity infections in patients with underlying conditions.
  • Prophylactic antibiotic therapy can be an effective strategy for reducing the recurrence of cellulitis in susceptible individuals.
  • Further research into optimal long-term antibiotic strategies for chronic lymphedema and stasis dermatitis patients is warranted.