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[Carotid endarterectomy in patients with coronary heart disease]
Erling Aarsaether1, Øystein K Moe, Per Erling Dahl
1Avdeling for hjerte-/lunge- og karkirurgi, Universitetssykehuset Nord-Norge, 9038 Tromsø. erling.johan.aarsaether@unn.no
Insights
Patients undergoing combined coronary artery bypass grafting (CABG) and carotid endarterectomy (CEA) have similar perioperative risks as those undergoing isolated CEA. This combined procedure is safe for patients with widespread atherosclerosis.
Area of Science:
- Cardiovascular Surgery
- Vascular Surgery
- Anesthesiology
Background:
- Patients with combined coronary and carotid artery disease face high stroke risk after CABG and myocardial infarction risk after CEA.
- Some institutions perform combined CABG and CEA during a single anesthetic period for symptomatic patients.
- This approach aims to mitigate risks associated with sequential procedures.
Purpose of the Study:
- To evaluate the perioperative safety and outcomes of combined CABG and CEA.
- To compare the risks of combined procedures with isolated CEA in patients with coronary artery disease.
Main Methods:
- Retrospective review of medical records for patients undergoing combined CABG and CEA (n=37) between 1986-2004.
- Comparison with patients undergoing isolated CEA (n=118) during the same period.
- Analysis of perioperative outcomes including stroke, myocardial infarction, and death.
Main Results:
- The combined procedure group had higher prevalence of peripheral artery disease, atrial fibrillation, and contralateral carotid occlusion.
- Stroke occurred in 5.4% of the combined group and 4.2% of the isolated CEA group.
- Perioperative myocardial infarction and 30-day mortality rates were similar between groups, with a lower cumulative risk in the combined group (8.1% vs 11.0%).
Conclusions:
- Combined CABG and CEA appears to have comparable perioperative risk to isolated CEA.
- This holds true despite a higher burden of generalized atherosclerotic disease in patients undergoing the combined procedure.
- The combined approach may be a safe option for select patients with severe coronary and carotid artery disease.
Background:
Patients with coexistent coronary and carotid artery disease are at high risk of developing stroke following coronary artery bypass grafting (CABG) and at the same time at increased risk of myocardial infarction when subjected to carotid endarterectomy (CEA). In patients with pronounced symptoms from both vascular territories, some institutions advocate a combined approach, with both CABG and CEA performed during the same period of anaesthesia.
Material And Methods:
We reviewed the medical records of patients who underwent the combined procedure between 1986 and 2004 (n = 37; group 1) and compared them to patients with coronary artery disease who underwent isolated CEA over the same period of time (n = 118; group 2).
Results:
The ASA score, NYHA class, prevalence of peripheral artery disease, atrial fibrillation and contralateral carotid occlusion were significantly higher in group 1. Two patients (5.4%) in group 1 and five patients (4.2%) in group 2 suffered a stroke. Five of these were ipsilateral to the CEA. Six patients had a perioperative myocardial infarction, one in group 1 (2.7%) and five (4.2%) in group 2 (ns). There were no deaths in group 1 and three deaths (2.5%) in group 2 during the first 30 days after surgery. The cumulative risk of death, stroke and myocardial infarction within 30 days was 8.1% in group 1 and 11.0% in group 2.
Interpretation:
Patients with coexistent atherosclerosis of the coronary and carotid arteries who underwent the combined procedure seem to have the same perioperative risk as patients with coronary artery disease who underwent isolated CEA, in spite of the fact that the former had a more generalised atherosclerotic disease.
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