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Exercise tolerance and hyperinsulinemia in cardiac syndrome X
Władysława Kolasilska-Kloch1, Wiktoria Leśniak, Iwona Leszczyńska-Gołabek
1II Klinika Kardiologii Instytutu Kardiologii, Collegium Medicum Uniwersytetu Jagiellońskiego.
Abstract:
The aim of the study was to evaluate the relationship between exercise tolerance, glucose and insulin levels and biochemical parameters related to endothelial function [endothelin-1 (ET-1), nitrite/nitrate (NOx)] in patients with cardiological syndrome X in comparison with healthy volunteers. The decrease of NOx level and NOx / ET-1 ratio suggests that endothelial dysfunction is present in cardiological syndrome X. Exercise tolerance correlated positively with NOx and negatively with insulin concentrations.
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