Comparison of measured resting energy expenditure versus predictive equations in pediatric burn patients

Many equations have been developed to estimate resting energy expenditure (REE) in thermally injured patients. A consensus has not been reached on the accuracy of these equations in children. The purpose of our study was to compare three predictive equations: Harris Benedict x 2 multiplier (HB x 2), Mayes (MG), and the WorId Health Organization x 2 multiplier (WHO x 2) with measured resting energy expenditure x I.3 multiplier (MREE x 1.3) in pediatric burn patients. MREE was measured by open-circuit indirect calorimetry in 10 burned children (6 boys, 4 girls) aged 2 to 10 years with TBSA burn ranges from 35% to 97%. MREE x 1.3 was compared with values obtained by HB x 2, MG, and WHO x 2 predictive equations. When comparing MREE x 1.3 with all three equations, significant differences were found when compared with HB x 2 and MG, but there were no significant difference between MREE x 1.3 vs WHO x 2. The HB x 2 and MG equations overpredicted MREE x 1.3 by 29% and 19%, respectively. Many predictive equations have been developed to predict energy expenditure in burns, but their accuracy in predicting MREE x 1.3 is variable. A larger study comparing/contrasting predictive equations and resting energy expenditure measured by indirect calorimetry is needed to improve the prediction of energy needs in burned children.