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TGF - β Signaling Pathway

TGF - β Signaling Pathway

The TGF-β signaling pathway regulates cell growth, differentiation, adhesion, motility, and development. TGF-β ligands that induce TGF-β signaling are synthesized in their latent form. Several proteases or cell surface receptors such as integrins act upon the latent form, releasing the active ligand. There are three types of mammalian TGF-βs: (TGF-β1, TGF-β2, and TGF-β3) that bind as homodimers or heterodimers to TGF-β receptors. The TGF-β receptors...

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Related Experiment Video

Updated: Jan 9, 2026

Visualization and Quantification of TGFβ/BMP/SMAD Signaling under Different Fluid Shear Stress Conditions using Proximity-Ligation-Assay

Visualization and Quantification of TGFβ/BMP/SMAD Signaling under Different Fluid Shear Stress Conditions using Proximity-Ligation-Assay

Published on: September 14, 2021

[Translational research using BMP family proteins]

Takashi Kaito¹, Akira Myoui, Hideki Yoshikawa

¹Department of Orthopaedics, Osaka University Graduate School of Medicine.

Nihon Rinsho. Japanese Journal of Clinical Medicine

|November 11, 2005

Summary

No abstract available in PubMed .

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