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Hypertension in HIV-infected patients: prevalence and related factors
Carlos Jericó1, Hernando Knobel, Milagro Montero
1Department of Medicine, Hospital del Mar, Universidad Autónoma de Barcelona, Barcelona, Spain.
Insights
Hypertension prevalence is similar in HIV-infected patients and controls. Key factors like age, BMI, and fat redistribution patterns, not combination antiretroviral therapy, are linked to hypertension in HIV patients.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- Hypertension prevalence and contributing factors in HIV-infected individuals remain under-researched.
- Understanding these factors is crucial for managing cardiovascular health in this population.
Purpose of the Study:
- To determine the prevalence of hypertension among HIV-infected patients.
- To identify factors associated with hypertension in the HIV-infected population.
Main Methods:
- Prospective cross-sectional study involving 710 HIV-infected patients and 802 controls.
- Data collection included medical examinations and a 6-month follow-up with three control visits.
Main Results:
- Hypertension prevalence was comparable: 13.1% in HIV patients and 13.5% in controls.
- Independent predictors of hypertension in HIV patients included age, body mass index, and lipoaccumulation pattern of fat redistribution.
Conclusions:
- No significant difference in hypertension prevalence was observed between HIV-infected individuals and controls.
- Combination antiretroviral therapy showed minimal impact on hypertension prevalence in this study.
Background:
Little is known about hypertension in the HIV-infected population. This study aimed to assess the prevalence of hypertension and related factors in HIV-infected patients.
Methods:
In this prospective cross-sectional study, 710 HIV-infected patients (626 on combination antiretroviral therapy and 84 naive) managed at the outpatient clinic of a tertiary hospital during 2003 and 802 controls completed the study protocol consisting of medical examination and a 6-month follow-up period including three control visits.
Results:
Hypertension prevalence was 13.1% in HIV-infected patients and 13.5% in the control group. Age (per 10-year increment) (odds ratio [OR]: 1.92; 95% confidence interval [CI]: 1.48-2.48), body mass index (OR: 1.18; 95% CI: 1.10-1.27), and lipoaccumulation pattern of fat redistribution (OR: 2.26; 95% CI: 1.20-4.24) were independently and significantly associated with the presence of hypertension in HIV-infected patients at logistic regression analysis.
Conclusions:
The present results suggest no meaningful difference in prevalence of hypertension between subjects with and without HIV infection. Thus, the influence of combination antiretroviral therapy appears to have little impact on the prevalence of hypertension.
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