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Clinical manifestations and functional outcomes in children with eosinophilic cystitis

R Houston Thompson1, Demetrius Dicks, Stephen A Kramer

  • 1Department of Urology, Mayo Medical School and Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

The Journal of Urology
|November 11, 2005
PubMed

Insights

Pediatric eosinophilic cystitis is rare, presenting with varied urinary symptoms and sometimes a bladder mass. Most cases resolve with conservative treatment, but some may require surgery.

Area of Science:

  • Pediatric Urology
  • Inflammatory Disorders
  • Oncology Mimics

Background:

  • Eosinophilic cystitis is an uncommon bladder inflammation with few reported pediatric cases.
  • This study reviews 20 years of experience with pediatric eosinophilic cystitis at a single institution.

Observation:

  • Four pediatric patients (ages 5-18) were diagnosed with eosinophilic cystitis.
  • Common symptoms included irritative voiding issues, hematuria, abdominal pain, and urinary tract infections.
  • Three patients had a history of allergic diseases; two showed positive allergen skin tests.
  • Two patients presented with bladder masses that mimicked malignancy.

Findings:

  • Mean patient age was 10.8 years, with a 3:1 male-to-female ratio.
  • Irritative urinary symptoms were universal.
  • Conservative management led to symptom resolution in three patients.
  • One patient developed a progressive tumefactive process requiring partial cystectomy and bladder augmentation.

Implications:

  • Eosinophilic cystitis presents diversely in children, including bladder masses mimicking cancer.
  • Biopsy is crucial for accurate diagnosis, differentiating it from oncological processes.
  • While often benign, the potential for unremitting disease necessitates careful monitoring and management.
Abstract

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