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Updated: Aug 14, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
[Acute juvenile pityriasis rubra pilaris in a 2-year-old child]
Adina Thölke1, Gabriele Feller, Dirk Schadendorf
1Klinik für Dermatologie, Venerologie und Allergologie am Klinikum Mannheim gGmbH, Universitätsklinikum der Ruprecht-Karls-Universität Heidelberg. adine.thoelke@haut.ma.uni-heidelberg.de
Abstract:
Pityriasis rubra pilaris (PRP) is a rare idiopathic erythematosquamous disorder. Griffiths proposed five clinical and prognostic forms: (1) classic adult, (2) atypical adult, (3) classic juvenile, (4) circumscribed juvenile and (5) atypical juvenile. A 2 1/2 year old boy presented with type 3 PRP; as is typical, the skin eruption was preceded by an infectious disorder. Although type 3 PRP normally shows spontaneous resolution after several months to years, our young patient had a severe and protracted course, only responding to systemic retinoids.
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