Related Experiment Video
Updated: Aug 5, 2026

Mouse Pneumonectomy Model of Compensatory Lung Growth
Published on: December 17, 2014
[Cardiovascular and respiratory complications after pneumonectomy]
B Izquierdo Villarroya1, S López Alvarez, C Bonome González
1Servicio de Anestesiología, Reanimación y Terapéutica del Dolor del Hospital Universitario Miguel Servet, Zaragoza. blizvi@comz.org
Pneumonectomy, a major thoracic surgery, still carries significant risks like heart and lung complications. This review synthesizes current literature to aid clinical decision-making for reducing these risks.
Area of Science:
- Cardiothoracic Surgery
- Anesthesiology
- Pulmonary Medicine
Context:
- Thoracic surgery, particularly pneumonectomy, faces challenges with high perioperative mortality and morbidity.
- Advances in anesthesia have improved outcomes, but specific risks post-pneumonectomy persist.
- Preoperative assessment is crucial for identifying high-risk patients, especially for cardiac complications.
Purpose:
- To review the literature on common complications following lung surgery, specifically pneumonectomy.
- To support clinical decision-making by integrating existing knowledge with clinical experience.
- To identify evidence gaps, such as optimal methods for assessing post-pneumonectomy lung function risk.
Summary:
- Pneumonectomy is associated with significant risks including cardiac complications (myocardial infarction 1.5-5%), arrhythmias, pulmonary edema (4-7%), and pneumonia.
- While prophylactic treatments are debated for arrhythmias and pneumonia, prevention is key for pulmonary edema.
- Optimal preoperative assessment for lung function impairment risk after pneumonectomy lacks clear evidence-based guidelines.
Impact:
- Aims to improve patient outcomes by providing a consolidated evidence base for managing pneumonectomy complications.
- Supports surgeons and anesthesiologists in making informed decisions for high-risk patients.
- Highlights areas needing further research to refine risk assessment and management strategies in thoracic surgery.
Related Concept Videos
Pneumonia III: Complications and Assessment
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Pneumothorax-I
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pneumothorax-II
Clinical Manifestations:
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Pneumothorax II: Pathophysiology

