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[Pulmonary pleomorphic carcinoma].

R Koga1, T Noriyuki, A Kimura

  • 1Department of Surgery, Yoshijima Hospital, Hiroshima, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|November 12, 2005
PubMed
Summary
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Pulmonary pleomorphic carcinoma is a rare lung cancer. This report details two surgical cases, one with fatal metastasis and another with successful resection, highlighting varied prognoses for this rare malignancy.

Area of Science:

  • Pulmonology
  • Oncology
  • Surgical Pathology

Background:

  • Pleomorphic carcinoma is a rare type of primary lung cancer.
  • Surgical resection is a primary treatment modality for resectable lung malignancies.

Observation:

  • Two cases of pulmonary pleomorphic carcinoma treated surgically are presented.
  • Case 1: A 71-year-old male with a rapidly growing tumor (Stage IIIA) who developed brain and mediastinal metastasis post-surgery.
  • Case 2: A 74-year-old male with a cavitary tumor (Stage IB) who showed no recurrence or metastasis 15 months after surgery.

Findings:

  • Pathological diagnosis confirmed pleomorphic carcinoma in both patients.
  • The patient with Stage IIIA disease experienced rapid progression and mortality.
  • The patient with Stage IB disease had a favorable outcome with no signs of recurrence.

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Implications:

  • Pulmonary pleomorphic carcinoma presents with variable clinical courses and prognoses.
  • Early-stage diagnosis and surgical intervention may improve outcomes.
  • Further research is needed to understand the biology and optimize treatment for this rare cancer.