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Published on: June 2, 2014
The effect of early intervention with sumatriptan tablets on migraine-associated productivity loss
W Jacqueline Kwong1, Frederick R Taylor, James U Adelman
1GlaxoSmithKline, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. jkwong@mail.rx.uga.edu
Objective:
Impaired performance, which can considerably impact employee output, occurs when employees attempt to continue work with inadequate treatment while experiencing a migraine episode. This analysis examined productivity loss as a result of migraine after treatment with sumatriptan tablets and patients' usual non-triptan therapy when pain was mild (early intervention) versus when pain was moderate/severe.
Methods:
The authors conducted a retrospective analysis of data on 6803 migraine days reported by 251 subjects who participated in a clinical trial.
Results:
Although early intervention significantly reduced productivity loss compared with treatment when pain was moderate/severe for both sumatriptan and non-triptan therapy, productivity loss was consistently lower for sumatriptan than non-triptan therapy for all predose pain intensity levels.
Conclusions:
These findings suggest that the pharmaco-economic benefits of early intervention with sumatriptan tablets, like the clinical benefits, exceed those of delayed intervention.