Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Evaluation of a hepatitis A immunization program.

Hesha Jani Duggirala1, Susan E Hassig, Sarah Santana

  • 1Tulane University, New Orleans, LA, USA. hcj@cdrh.fda.gov

The Pediatric Infectious Disease Journal
|November 12, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identification and Evaluations of Novel Insecticidal Proteins from Plants of the Class Polypodiopsida for Crop Protection against Key Lepidopteran Pests.

Toxins·2019
Same author

Development of a Direct Observation Instrument to Measure Environmental Characteristics of Parks for Physical Activity.

Journal of physical activity & health·2017
Same author

Implementation of a mental health consultation model and its impact on early childhood teachers' efficacy and competence.

Infant mental health journal·2017
Same author

Species-based comparison of disease severity and risk factors for disseminated Candida infections in pediatric patients.

Infection and drug resistance·2016
Same author

Youth walking and biking rates vary by environments around 5 Louisiana schools.

The Journal of school health·2014
Same author

Sex differences in nutritional status of HIV-exposed children in Rwanda: a longitudinal study.

Tropical medicine & international health : TM & IH·2014

A hepatitis A vaccine requirement for child-care attendees in Maricopa County reduced disease risk. Post-vaccination, child-care centers were no longer a significant source of hepatitis A transmission.

Area of Science:

  • Epidemiology
  • Vaccinology
  • Public Health

Background:

  • Child-care centers were identified as a significant source of hepatitis A transmission in Maricopa County prior to 1997.
  • A previous case-control study indicated that 40% of hepatitis A cases were linked to child-care settings.

Purpose of the Study:

  • To assess the effectiveness of a mandatory hepatitis A vaccination policy for child-care attendees aged 2-5 years.
  • To determine if the association between child-care centers and hepatitis A cases persisted after vaccine implementation.

Main Methods:

  • A case-control study was conducted in 1999, comparing individuals meeting the Centers for Disease Control and Prevention (CDC) hepatitis A case definition with matched controls.
  • 72 cases and 144 controls were recruited and matched based on age and neighborhood.

Related Experiment Videos

Main Results:

  • Contact with a hepatitis A case was associated with increased disease risk (OR 5.63).
  • Individuals with direct child-care center contact showed a protective effect against hepatitis A (OR 0.221).
  • Education was also found to have a significant protective effect (OR 0.19).

Conclusions:

  • The hepatitis A vaccination requirement appears to have influenced the disease's epidemiology in Maricopa County.
  • The significant risk associated with child-care centers observed in 1997 was no longer evident post-vaccination policy implementation.