Related Experiment Video

Updated: Jul 25, 2026

High-Throughput, Multi-Image Cryohistology of Mineralized Tissues
10:18

High-Throughput, Multi-Image Cryohistology of Mineralized Tissues

Published on: September 14, 2016

Recent progress in histochemistry and cell biology: the state of the art 2005

Douglas J Taatjes1, Jürgen Roth

  • 1Microscopy Imaging Center, Department of Pathology, College of Medicine, University of Vermont, Burlington, VT 05405, USA. douglas.taatjes@uvm.edu

Histochemistry and Cell Biology
|November 12, 2005
PubMed

More Related Videos

Digital Analysis of Immunostaining of ZW10 Interacting Protein in Human Lung Tissues07:40

Digital Analysis of Immunostaining of ZW10 Interacting Protein in Human Lung Tissues

Published on: May 1, 2019

Histological-Based Stainings Using Free-Floating Tissue Sections06:45

Histological-Based Stainings Using Free-Floating Tissue Sections

Published on: August 25, 2020

Related Concept Videos

Studying the Cytoskeleton01:17

Studying the Cytoskeleton

The cytoskeletal architecture can be studied using different microscopic and biochemical techniques. Electron microscopy was instrumental in discovering the cytoskeletal architecture around the 1960s, which allowed obtaining structural information at a high-resolution level. However, the sample preparation procedure often limits this ability in biological samples. Several protocols have been developed over the years to optimize sample preparation. In one of the protocols known as rotary...
In-situ Hybridization02:31

In-situ Hybridization

In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
Types of probes and labels
A probe is a complementary strand of DNA or RNA that binds to corresponding nucleotide sequences in a cell. Many...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Subcellular Fractionation01:32

Subcellular Fractionation

The homogenate obtained after cell lysis contains various membrane-bound organelles that can be further separated into pure fractions by subcellular fractionation. These isolates are used to study specific cellular components, analyze localized protein activity, and are even employed in diagnostics. Fractionation is typically achieved using centrifugation methods, the most common being density-gradient and differential centrifugation.
Differential Centrifugation
Differential centrifugation is...
Immunocytochemistry and Immunohistochemistry01:22

Immunocytochemistry and Immunohistochemistry

Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
These...