Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Paraneoplastic limbic encephalitis presenting as acute viral encephalitis.

E Kararizou, I Markou, I Zalonis

    Journal of Neuro-Oncology
    |November 12, 2005
    PubMed
    Summary

    This case study highlights a rare instance where limbic encephalitis (LE) mimicked a viral infection but was linked to an undiagnosed renal carcinoma. Early diagnosis and treatment are crucial for managing this complex neurological condition.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Haemophagocytic lymphohistiocytosis after intravesical BCG administration for bladder cancer presenting with multiorgan failure.

    Access microbiology·2023
    Same author

    Objective and Subjective Measurements of Motor Function: Results from the HELIAD Study.

    The journal of prevention of Alzheimer's disease·2022
    Same author

    Sex Differences in Frailty Incidence in Greek Community-Dwelling Older People: The HELIAD Study.

    The Journal of frailty & aging·2022
    Same author

    Outcome of refractory to conventional and/or biologic treatment adult Still's disease following canakinumab treatment: Countrywide data in 50 patients.

    Seminars in arthritis and rheumatism·2020
    Same author

    Treatment modalities and drug survival in a systemic sclerosis real-life patient cohort.

    Arthritis research & therapy·2020
    Same author

    Skew deviation after blunt head trauma.

    Revue neurologique·2020

    Area of Science:

    • Neurology
    • Oncology
    • Infectious Diseases

    Background:

    • Limbic encephalitis (LE) is an inflammatory condition affecting the limbic system.
    • It can present with diverse neurological symptoms, often mimicking infectious or autoimmune processes.
    • Distinguishing the underlying cause is critical for effective management.

    Observation:

    • A patient initially presenting with symptoms suggestive of viral limbic encephalitis (LE) developed severe neurological decline.
    • Cerebrospinal fluid analysis supported a viral etiology, while MRI revealed limbic system abnormalities.
    • Subsequent clinical evaluation unexpectedly identified an underlying renal carcinoma.

    Findings:

    • The patient experienced fever, seizures, altered consciousness, and agitation, consistent with limbic encephalitis.

    Related Experiment Videos

  • Despite initial presentation resembling viral LE, a renal carcinoma was diagnosed during the workup.
  • Nephrectomy was performed following the diagnosis of renal carcinoma.

    • Implications:

    • This case underscores the importance of comprehensive evaluation in limbic encephalitis, as paraneoplastic syndromes can present atypically.
    • The association between limbic encephalitis and renal carcinoma highlights the need to consider malignancy in unexplained neurological cases.
    • Prompt diagnosis and treatment of both the neurological condition and the underlying cancer are essential for improved patient outcomes.