[Interfollicular Hodgkin's disease]

Two cases of so-called interfollicular Hodgkin's disease, one case lacking of all histological criteria and one case of lymphadenitis mimicking Hodgkin's disease, were identified among 76 patients with Hodgkin's disease. Case 1 and 2 rank among lymphocyte predominance type, case 3 showed mixed cellularity. They shared a progressive transformation of germinal centres which was proved by immunohistology. Leu M 1 antibody-positive cells were found in both cases of the so-called interfollicular Hodgkin's disease and not in lymphadenitis mimicking Hodgkin's disease.