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Related Experiment Videos

Split hand foot malformation (SHFM).

A M Elliott1, J A Evans, A E Chudley

  • 1Department of Biochemistry and Medical Genetics, University of Manitoba, Canada.

Clinical Genetics
|November 15, 2005
PubMed
Summary
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The nomenclature for split hand/foot malformation (SHFM) is confusing, with varied terms used across genetics and surgical fields. This review clarifies SHFM terminology and classifications for better understanding.

Area of Science:

  • Genetics
  • Developmental Biology
  • Clinical Medicine

Background:

  • The phenotype of missing central hand/foot rays has inconsistent terminology in scientific literature.
  • Terms like 'lobster-claw malformation' and 'ectrodactyly' are used alongside the preferred 'split hand/foot malformation' (SHFM).
  • This naming inconsistency complicates research and clinical communication.

Purpose of the Study:

  • To review and clarify the heterogeneous nomenclature associated with split hand/foot malformation (SHFM).
  • To provide a consolidated overview of the terms used to describe this limb malformation.
  • To promote standardized terminology in genetics and surgical fields.

Main Methods:

  • Literature review of scientific articles and clinical reports.

Related Experiment Videos

  • Analysis of terminology used in genetics and surgical contexts.
  • Comparison of different nomenclature systems for limb malformations.

    • Main Results:

    • Split hand/foot malformation (SHFM) is the most prevalent term in genetics.
    • Older, less precise, or offensive terms like 'ectrodactyly' and 'lobster-claw malformation' persist.
    • Significant heterogeneity exists in the naming conventions for this phenotype.

    Conclusions:

    • Standardizing nomenclature for SHFM is crucial for clear scientific communication.
    • Adoption of consistent terminology will aid in research and clinical diagnosis.
    • Further efforts are needed to eliminate confusing and outdated terms.